"Reports of My Death Were Greatly Exaggerated": Behavior Genetics in the Postgenomic Era.
Annu Rev Psychol
; 72: 37-60, 2021 01 04.
Article
in En
| MEDLINE
| ID: mdl-32898465
ABSTRACT
Behavior genetics studies how genetic differences among people contribute to differences in their psychology and behavior. Here, I describe how the conclusions and methods of behavior genetics have evolved in the postgenomic era in which the human genome can be directly measured. First, I revisit the first law of behavioral genetics stating that everything is heritable, and I describe results from large-scale meta-analyses of twin data and new methods for estimating heritability using measured DNA. Second, I describe new methods in statistical genetics, including genome-wide association studies and polygenic score analyses. Third, I describe the next generation of work on gene × environment interaction, with a particular focus on how genetic influences vary across sociopolitical contexts and exogenous environments. Genomic technology has ushered in a golden age of new tools to address enduring questions about how genes and environments combine to create unique human lives.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Genetics, Behavioral
Limits:
Humans
Language:
En
Journal:
Annu Rev Psychol
Year:
2021
Type:
Article