Design of experiments guided multivariate calibration for the quantitation of injectable colistimethate sodium by ultra performance liquid chromatography - High resolution mass spectrometry.

Dagla, Ioanna; Tsarbopoulos, Anthony; Gikas, Evagelos

Dagla, Ioanna; Tsarbopoulos, Anthony; Gikas, Evagelos.

Affiliation

Dagla I; Laboratory of Pharmaceutical Analysis, Division of Pharmaceutical Chemistry, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistiomiopolis, Zografou, 157 71, Athens, Greece.
Tsarbopoulos A; Laboratory of Pharmacology, Department of Descriptive-Functional Studies, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Gikas E; Laboratory of Analytical Chemistry, School of Chemistry, National and Kapodistrian University of Athens, Panepistiomiopolis, Zografou, 157 71, Athens, Greece. Electronic address: vgikas@chem.uoa.gr.

Talanta ; 220: 121406, 2020 Dec 01.

Article in En | MEDLINE | ID: mdl-32928422

Subject(s)

Chromatography, High Pressure Liquid; Calibration; Chromatography, Liquid; Colistin/analogs & derivatives; Gas Chromatography-Mass Spectrometry; Mass Spectrometry

Key words

Colistimethate; Mass spectrometry; Multivariate analysis; Partial least square regression; Pharmaceutical products; Quality control

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, High Pressure Liquid Type of study: Prognostic_studies Language: En Journal: Talanta Year: 2020 Type: Article Affiliation country: Greece

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