Whole-brain computational modeling reveals disruption of microscale brain dynamics in HIV infected individuals.

Zhuang, Yuchuan; Zhang, Zhengwu; Tivarus, Madalina; Qiu, Xing; Zhong, Jianhui; Schifitto, Giovanni

Zhuang, Yuchuan; Zhang, Zhengwu; Tivarus, Madalina; Qiu, Xing; Zhong, Jianhui; Schifitto, Giovanni.

Affiliation

Zhuang Y; Department of Electrical and Computer Engineering, University of Rochester, Rochester, New York, USA.
Zhang Z; Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York, USA.
Tivarus M; Department of Neuroscience, University of Rochester Medical Center, Rochester, New York, USA.
Qiu X; Department of Neuroscience, University of Rochester Medical Center, Rochester, New York, USA.
Zhong J; Department of Imaging Sciences, University of Rochester Medical Center, Rochester, New York, USA.
Schifitto G; Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York, USA.

Hum Brain Mapp ; 42(1): 95-109, 2021 01.

Article in En | MEDLINE | ID: mdl-32941693

Subject(s)

Brain; Default Mode Network; HIV Infections; Magnetic Resonance Imaging/methods; Models, Theoretical; Nerve Net; Neuroimaging/methods; Adult; Antiretroviral Therapy, Highly Active; Brain/diagnostic imaging; Brain/pathology; Brain/physiopathology; Connectome; Default Mode Network/diagnostic imaging; Default Mode Network/pathology; Default Mode Network/physiopathology; Diffusion Tensor Imaging; Echo-Planar Imaging; Female; Follow-Up Studies; HIV Infections/diagnostic imaging; HIV Infections/drug therapy; HIV Infections/pathology; HIV Infections/physiopathology; Humans; Male; Nerve Net/diagnostic imaging; Nerve Net/pathology; Nerve Net/physiopathology

Key words

HIV-infection; graph theoretical analysis; resting-state functional MRI; tractography; whole-brain computational modeling

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Magnetic Resonance Imaging / HIV Infections / Neuroimaging / Default Mode Network / Models, Theoretical / Nerve Net Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Hum Brain Mapp Journal subject: CEREBRO Year: 2021 Type: Article Affiliation country: United States

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