Identification of Specific <i>N</i><sup>6</sup>-Methyladenosine RNA Demethylase FTO Inhibitors by Single-Quantum-Dot-Based FRET Nanosensors.

Zhang, Yan; Li, Qing-Nan; Zhou, Kaiyue; Xu, Qinfeng; Zhang, Chun-Yang

Identification of Specific N⁶-Methyladenosine RNA Demethylase FTO Inhibitors by Single-Quantum-Dot-Based FRET Nanosensors.

Zhang, Yan; Li, Qing-Nan; Zhou, Kaiyue; Xu, Qinfeng; Zhang, Chun-Yang.

Affiliation

Zhang Y; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of F
Li QN; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of F
Zhou K; School of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an 710021, P. R. China.
Xu Q; School of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an 710021, P. R. China.
Zhang CY; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of F

Anal Chem ; 92(20): 13936-13944, 2020 10 20.

Article in En | MEDLINE | ID: mdl-32972135

Subject(s)

Alpha-Ketoglutarate-Dependent Dioxygenase FTO/antagonists & inhibitors; Biosensing Techniques/methods; Enzyme Inhibitors/chemistry; Fluorescence Resonance Energy Transfer; Quantum Dots/chemistry; Adenosine/analogs & derivatives; Adenosine/chemistry; Alpha-Ketoglutarate-Dependent Dioxygenase FTO/genetics; Alpha-Ketoglutarate-Dependent Dioxygenase FTO/metabolism; Anthraquinones/chemistry; Anthraquinones/metabolism; Binding Sites; Carbocyanines/chemistry; Catalytic Domain; DNA Demethylation; Enzyme Inhibitors/metabolism; HeLa Cells; Humans; Molecular Dynamics Simulation; RNA, Messenger/chemistry; RNA, Messenger/metabolism; RNA, Small Interfering/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biosensing Techniques / Fluorescence Resonance Energy Transfer / Quantum Dots / Enzyme Inhibitors / Alpha-Ketoglutarate-Dependent Dioxygenase FTO Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Anal Chem Year: 2020 Type: Article

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