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A pilot clinical trial of the cytidine deaminase inhibitor tetrahydrouridine combined with decitabine to target DNMT1 in advanced, chemorefractory pancreatic cancer.
Sohal, Davendra; Krishnamurthi, Smitha; Tohme, Rita; Gu, Xiaorong; Lindner, Daniel; Landowski, Terry H; Pink, John; Radivoyevitch, Tomas; Fada, Sherry; Lee, Zhenghong; Shepard, Dale; Khorana, Alok; Saunthararajah, Yogen.
Affiliation
  • Sohal D; Division of Hematology and Oncology, University of Cincinnati Cincinnati, Ohio, USA.
  • Krishnamurthi S; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic Cleveland, Ohio, USA.
  • Tohme R; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Cleveland, Ohio, USA.
  • Gu X; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Cleveland, Ohio, USA.
  • Lindner D; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Cleveland, Ohio, USA.
  • Landowski TH; Department of Medicine, University of Arizona Tucson, Arizona, USA.
  • Pink J; Translational Research Shared Resource, Case Comprehensive Cancer Center, Case Western Reserve University Cleveland, Ohio, USA.
  • Radivoyevitch T; Department of Quantitative Health Sciences, Cleveland Clinic Cleveland, Ohio, USA.
  • Fada S; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Cleveland, Ohio, USA.
  • Lee Z; Department of Biomedical Engineering, Case Western Reserve University Cleveland, Ohio, USA.
  • Shepard D; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic Cleveland, Ohio, USA.
  • Khorana A; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic Cleveland, Ohio, USA.
  • Saunthararajah Y; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic Cleveland, Ohio, USA.
Am J Cancer Res ; 10(9): 3047-3060, 2020.
Article in En | MEDLINE | ID: mdl-33042633
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Am J Cancer Res Year: 2020 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Am J Cancer Res Year: 2020 Type: Article Affiliation country: United States