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Liposomal FRET Assay Identifies Potent Drug-Like Inhibitors of the Ceramide Transport Protein (CERT).
Samaha, Doaa; Hamdo, Housam H; Cong, Xiaojing; Schumacher, Fabian; Banhart, Sebastian; Aglar, Öznur; Möller, Heiko M; Heuer, Dagmar; Kleuser, Burkhard; Saied, Essa M; Arenz, Christoph.
Affiliation
  • Samaha D; Insitute for Chemistry, Humboldt Universität zu Berlin, Brook-Taylor-Strasse 2, 12489, Berlin, Germany.
  • Hamdo HH; Department of Pharmaceutical Chemistry, College of Pharmacy, Helwan University, Cairo, 11795, Egypt.
  • Cong X; Insitute for Chemistry, Humboldt Universität zu Berlin, Brook-Taylor-Strasse 2, 12489, Berlin, Germany.
  • Schumacher F; CNRS, Institut de Chimie de Nice, Université Côte d'Azur, 06108, Nice, France.
  • Banhart S; Department of Toxicology, Institute of Nutritional Science, University of Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany.
  • Aglar Ö; Department of Molecular Biology, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.
  • Möller HM; Unit 'Sexually Transmitted Bacterial Infections', Department of Infectious Diseases, Robert Koch Institute, 13353, Berlin, Germany.
  • Heuer D; Universität Potsdam, Institut für Chemie, Karl- Liebknecht- Strasse 24-25, Haus 25, 14476, Golm, Germany.
  • Kleuser B; Universität Potsdam, Institut für Chemie, Karl- Liebknecht- Strasse 24-25, Haus 25, 14476, Golm, Germany.
  • Saied EM; Unit 'Sexually Transmitted Bacterial Infections', Department of Infectious Diseases, Robert Koch Institute, 13353, Berlin, Germany.
  • Arenz C; Department of Toxicology, Institute of Nutritional Science, University of Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany.
Chemistry ; 26(70): 16616-16621, 2020 Dec 15.
Article in En | MEDLINE | ID: mdl-33047409
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Carrier Proteins / Ceramides / Fluorescence Resonance Energy Transfer / Drug Evaluation, Preclinical Limits: Animals / Humans Language: En Journal: Chemistry Journal subject: QUIMICA Year: 2020 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Carrier Proteins / Ceramides / Fluorescence Resonance Energy Transfer / Drug Evaluation, Preclinical Limits: Animals / Humans Language: En Journal: Chemistry Journal subject: QUIMICA Year: 2020 Type: Article Affiliation country: Germany