Agranulocytosis-complicated DRESS with medullar HHV-6 replication.

Lehericey, Margot; Tétart, Florence; Carvalho, Priscille; Bauvin, Olivia; Hervouet, Charles; Joly, Pascal; Hébert, Vivien

Lehericey, Margot; Tétart, Florence; Carvalho, Priscille; Bauvin, Olivia; Hervouet, Charles; Joly, Pascal; Hébert, Vivien.

Affiliation

Lehericey M; Department of Dermatology Caen University Hospital Caen France.
Tétart F; Department of Dermatology Rouen University Hospital Rouen France.
Carvalho P; Allergology Center Erik Satie Rouen University Hospital Rouen France.
Bauvin O; Department of Dermatology Rouen University Hospital Rouen France.
Hervouet C; Department of Dermatology Rouen University Hospital Rouen France.
Joly P; Pharmacy Department Rouen University Hospital Rouen France.
Hébert V; Department of Dermatology Rouen University Hospital Rouen France.

Clin Case Rep ; 8(10): 1928-1931, 2020 Oct.

Article in En | MEDLINE | ID: mdl-33088521

ABSTRACT

HHV-6B is the subtype most often involved in the systemic manifestations of the DRESS, but also in myelosuppression in bone marrow transplant. We report a new observation of its myelosuppressive effect: a case of DRESS complicated by agranulocytosis with detectable HHV-6 RNA in bone marrow.

Key words

HHV6; agranulocytosis; bone marrow; drug reaction with eosinophilia and systemic symptoms

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