Connexin43 is differentially distributed within renal vasculature and mediates profibrotic differentiation in medullary fibroblasts.

Xu, Yan; Hu, Junda; Yilmaz, Duygu Elif; Bachmann, Sebastian

Xu, Yan; Hu, Junda; Yilmaz, Duygu Elif; Bachmann, Sebastian.

Affiliation

Xu Y; Department of Anatomy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Hu J; Department of Anatomy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Yilmaz DE; Department of Anatomy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Bachmann S; Department of Anatomy, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Am J Physiol Renal Physiol ; 320(1): F17-F30, 2021 01 01.

Article in En | MEDLINE | ID: mdl-33196322

Subject(s)

Cell Differentiation; Connexin 43/metabolism; Endothelial Cells/metabolism; Fibroblasts/metabolism; Kidney Medulla/blood supply; Kidney Medulla/metabolism; Animals; Cell Communication; Cell Line; Endothelial Cells/ultrastructure; Fibroblasts/ultrastructure; Fibrosis; Gap Junctions/metabolism; Gap Junctions/ultrastructure; Humans; Kidney Medulla/ultrastructure; Male; Mice, Inbred C57BL; Myofibroblasts/metabolism; Myofibroblasts/ultrastructure; Phenotype; Rats, Wistar

Key words

connexon; fibrosis; intima; renomedullary interstitial cell; transforming growth factor-ß1

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Differentiation / Connexin 43 / Endothelial Cells / Fibroblasts / Kidney Medulla Limits: Animals / Humans / Male Language: En Journal: Am J Physiol Renal Physiol Journal subject: FISIOLOGIA / NEFROLOGIA Year: 2021 Type: Article Affiliation country: Germany

Fulltext

XML

PubMed Links

Search on Google