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Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies.
Beaumont, Robin N; Kotecha, Sarah J; Wood, Andrew R; Knight, Bridget A; Sebert, Sylvain; McCarthy, Mark I; Hattersley, Andrew T; Järvelin, Marjo-Riitta; Timpson, Nicholas J; Freathy, Rachel M; Kotecha, Sailesh.
Affiliation
  • Beaumont RN; Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.
  • Kotecha SJ; Department of Child Health, School of Medicine, Cardiff University, Cardiff, United Kingdom.
  • Wood AR; Department of Child Health, School of Medicine, Cardiff University, Cardiff, United Kingdom.
  • Knight BA; Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.
  • Sebert S; Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.
  • McCarthy MI; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulun yliopisto, Finland.
  • Hattersley AT; Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland.
  • Järvelin MR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Timpson NJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom.
  • Freathy RM; Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom.
  • Kotecha S; Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.
PLoS Genet ; 16(12): e1009191, 2020 12.
Article in En | MEDLINE | ID: mdl-33284794
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Birth Weight / Multifactorial Inheritance Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Newborn Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2020 Type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Birth Weight / Multifactorial Inheritance Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Newborn Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2020 Type: Article Affiliation country: United kingdom