Multiple Sclerosis-Like Symptoms in Mice Are Driven by Latent Î³Herpesvirus-68 Infected B Cells.

Márquez, Ana Citlali; Shanina, Iryna; Horwitz, Marc Steven

Márquez, Ana Citlali; Shanina, Iryna; Horwitz, Marc Steven.

Affiliation

Márquez AC; Department of Microbiology and Immunology, The University of British Columbia, Vancouver, BC, Canada.
Shanina I; Department of Microbiology and Immunology, The University of British Columbia, Vancouver, BC, Canada.
Horwitz MS; Department of Microbiology and Immunology, The University of British Columbia, Vancouver, BC, Canada.

Front Immunol ; 11: 584297, 2020.

Article in En | MEDLINE | ID: mdl-33329556

Subject(s)

B-Lymphocytes/immunology; Epstein-Barr Virus Infections/immunology; Herpesvirus 4, Human/immunology; Multiple Sclerosis/immunology; Multiple Sclerosis/virology; Animals; Antigen-Presenting Cells/immunology; Autoimmunity/immunology; Brain/immunology; Encephalomyelitis, Autoimmune, Experimental/immunology; Encephalomyelitis, Autoimmune, Experimental/virology; Mice; Mice, Inbred C57BL; Paracrine Communication/immunology; Signal Transduction/immunology; Th1 Cells/immunology

Key words

B cells; EAE; Epstein-Barr Virus; environmental factors; multiple sclerosis; Î³HV-68

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Herpesvirus 4, Human / Epstein-Barr Virus Infections / Multiple Sclerosis Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Front Immunol Year: 2020 Type: Article Affiliation country: Canada

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