Safety and Efficacy of Lemborexant in Patients With Irregular Sleep-Wake Rhythm Disorder and Alzheimer's Disease Dementia: Results From a Phase 2 Randomized Clinical Trial.

Moline, M; Thein, S; Bsharat, M; Rabbee, N; Kemethofer-Waliczky, M; Filippov, G; Kubota, N; Dhadda, S

Moline, M; Thein, S; Bsharat, M; Rabbee, N; Kemethofer-Waliczky, M; Filippov, G; Kubota, N; Dhadda, S.

Affiliation

Moline M; Margaret Moline, PhD, Clinical Research, Eisai, Inc., 100 Tice Boulevard, Woodcliff Lake, NJ 07677, USA, Phone: +1 (201) 949-4226, Fax: +1 (201) 949-4595, E-mail: Margaret_Moline@eisai.com.

J Prev Alzheimers Dis ; 8(1): 7-18, 2021.

Article in En | MEDLINE | ID: mdl-33336219

Subject(s)

Alzheimer Disease/complications; Circadian Rhythm/drug effects; Orexin Receptor Antagonists/administration & dosage; Pyridines/administration & dosage; Pyrimidines/administration & dosage; Sleep Wake Disorders/drug therapy; Actigraphy/methods; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Male; Middle Aged; Orexin Receptor Antagonists/pharmacology; Pyridines/pharmacology; Pyrimidines/pharmacology; Sleep Wake Disorders/etiology

Key words

Alzheimer's disease; Irregular sleep-wake rhythm disorder; lemborexant

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Pyrimidines / Sleep Wake Disorders / Circadian Rhythm / Alzheimer Disease / Orexin Receptor Antagonists Type of study: Clinical_trials / Etiology_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Prev Alzheimers Dis Year: 2021 Type: Article

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