Mistargeting of secretory cargo in retromer-deficient cells.

Neuman, Sarah D; Terry, Erica L; Selegue, Jane E; Cavanagh, Amy T; Bashirullah, Arash

Neuman, Sarah D; Terry, Erica L; Selegue, Jane E; Cavanagh, Amy T; Bashirullah, Arash.

Affiliation

Neuman SD; Division of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI 53705-2222, USA.
Terry EL; Division of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI 53705-2222, USA.
Selegue JE; Division of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI 53705-2222, USA.
Cavanagh AT; Division of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI 53705-2222, USA.
Bashirullah A; Division of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI 53705-2222, USA.

Dis Model Mech ; 14(1)2021 01 01.

Article in En | MEDLINE | ID: mdl-33380435

Subject(s)

Drosophila melanogaster/genetics; Drosophila/physiology; Salivary Glands/metabolism; rab7 GTP-Binding Proteins/metabolism; Amyloid beta-Protein Precursor/metabolism; Animals; Biological Transport; Disease Models, Animal; Disease Progression; Drosophila melanogaster/metabolism; Endosomes/metabolism; Exocytosis/physiology; Lysosomes/metabolism; Microscopy, Confocal; Neurodegenerative Diseases/metabolism; Phenotype; Protein Transport; Secretory Vesicles/metabolism

Key words

Drosophila; Vps26; Regulated exocytosis; Retromer; Salivary gland; Secretory granule

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salivary Glands / Drosophila / Drosophila melanogaster / Rab7 GTP-Binding Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2021 Type: Article Affiliation country: United States

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