Interferon-related gene expression in response to TNF inhibitor treatment in ankylosing spondylitis patients: a pilot study.

Harrison, Stephanie R; Burska, Agata N; Emery, Paul; Marzo-Ortega, Helena; Ponchel, Frederique

Harrison, Stephanie R; Burska, Agata N; Emery, Paul; Marzo-Ortega, Helena; Ponchel, Frederique.

Affiliation

Harrison SR; University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, UK.
Burska AN; University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, UK.
Emery P; University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, UK.
Marzo-Ortega H; NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Ponchel F; University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, UK.

Rheumatology (Oxford) ; 60(8): 3607-3616, 2021 08 02.

Article in En | MEDLINE | ID: mdl-33393636

Subject(s)

Gene Expression Regulation/drug effects; Interferon Type I/metabolism; Spondylitis, Ankylosing/blood; Tumor Necrosis Factor Inhibitors/therapeutic use; Adult; Aged; Biomarkers/blood; Female; Humans; Interleukin-6/blood; Male; Middle Aged; Pilot Projects; Spondylitis, Ankylosing/drug therapy; Tumor Necrosis Factor Inhibitors/pharmacology; Young Adult

Key words

ankylosing spondylitis; axial spondyloarthritis; gene expression signature; interferon; tumour necrosis factor inhibitor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spondylitis, Ankylosing / Interferon Type I / Gene Expression Regulation / Tumor Necrosis Factor Inhibitors Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Rheumatology (Oxford) Journal subject: REUMATOLOGIA Year: 2021 Type: Article Affiliation country: United kingdom

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