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D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction.
Gobeil, Sophie M-C; Janowska, Katarzyna; McDowell, Shana; Mansouri, Katayoun; Parks, Robert; Manne, Kartik; Stalls, Victoria; Kopp, Megan F; Henderson, Rory; Edwards, Robert J; Haynes, Barton F; Acharya, Priyamvada.
Affiliation
  • Gobeil SM; Duke Human Vaccine Institute, Durham, NC 27710, USA.
  • Janowska K; Duke Human Vaccine Institute, Durham, NC 27710, USA.
  • McDowell S; Duke Human Vaccine Institute, Durham, NC 27710, USA.
  • Mansouri K; Duke Human Vaccine Institute, Durham, NC 27710, USA.
  • Parks R; Duke Human Vaccine Institute, Durham, NC 27710, USA.
  • Manne K; Duke Human Vaccine Institute, Durham, NC 27710, USA.
  • Stalls V; Duke Human Vaccine Institute, Durham, NC 27710, USA.
  • Kopp MF; Duke Human Vaccine Institute, Durham, NC 27710, USA.
  • Henderson R; Duke Human Vaccine Institute, Durham, NC 27710, USA; Department of Medicine, Duke University, Durham, NC 27710, USA.
  • Edwards RJ; Duke Human Vaccine Institute, Durham, NC 27710, USA; Department of Medicine, Duke University, Durham, NC 27710, USA.
  • Haynes BF; Duke Human Vaccine Institute, Durham, NC 27710, USA; Department of Medicine, Duke University, Durham, NC 27710, USA; Department of Immunology, Duke University, Durham NC 27710, USA.
  • Acharya P; Duke Human Vaccine Institute, Durham, NC 27710, USA; Department of Surgery, Duke University, Durham NC 27710, USA. Electronic address: priyamvada.acharya@duke.edu.
Cell Rep ; 34(2): 108630, 2021 01 12.
Article in En | MEDLINE | ID: mdl-33417835
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Hydrolases / Spike Glycoprotein, Coronavirus / SARS-CoV-2 Limits: Humans Language: En Journal: Cell Rep Year: 2021 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Hydrolases / Spike Glycoprotein, Coronavirus / SARS-CoV-2 Limits: Humans Language: En Journal: Cell Rep Year: 2021 Type: Article Affiliation country: United States