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Computationally reconstructing cotranscriptional RNA folding from experimental data reveals rearrangement of non-native folding intermediates.
Yu, Angela M; Gasper, Paul M; Cheng, Luyi; Lai, Lien B; Kaur, Simi; Gopalan, Venkat; Chen, Alan A; Lucks, Julius B.
Affiliation
  • Yu AM; Tri-Institutional Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10065, USA; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60201, USA.
  • Gasper PM; Department of Chemistry and the RNA Institute, University at Albany, Albany, NY 12222, USA.
  • Cheng L; Interdisciplinary Biological Sciences Graduate Program, Northwestern University, Evanston, IL 60201, USA.
  • Lai LB; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA; Center for RNA Biology, The Ohio State University, Columbus, OH 43210, USA.
  • Kaur S; Department of Chemistry and the RNA Institute, University at Albany, Albany, NY 12222, USA.
  • Gopalan V; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA; Center for RNA Biology, The Ohio State University, Columbus, OH 43210, USA.
  • Chen AA; Department of Chemistry and the RNA Institute, University at Albany, Albany, NY 12222, USA. Electronic address: achen6@albany.edu.
  • Lucks JB; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60201, USA. Electronic address: jblucks@northwestern.edu.
Mol Cell ; 81(4): 870-883.e10, 2021 02 18.
Article in En | MEDLINE | ID: mdl-33453165
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Bacterial / Signal Recognition Particle / Escherichia coli Proteins / Ribonuclease P / Escherichia coli / RNA Folding Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Bacterial / Signal Recognition Particle / Escherichia coli Proteins / Ribonuclease P / Escherichia coli / RNA Folding Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: United States