The effect of phototherapy on sleep during acute rehabilitation after traumatic brain injury: a randomized controlled trial.
Brain Inj
; 35(2): 180-188, 2021 01 18.
Article
in En
| MEDLINE
| ID: mdl-33459040
ABSTRACT
Objective:
To examine the impact of bright white light (BWL) exposure on sleep quality in persons with recent traumatic brain injury (TBI).Design:
Randomized, controlled device-sham studySetting:
3 TBI Model System inpatient rehabilitation unitsParticipants:
131 participants (mean 40.9 years, 68% male)Intervention Intervention group (N = 65) received BWL (1260 lux at 20 inches, 440-480 nanometers length) for 30 minutes each morning at 12-24 inches from the face. Control group (N = 66) received red light (<450 lux, no light between 440 and 480 nanometers) for the same period. Planned intervention was maximum of 10 treatments or until discharge.Main OutcomeMeasure:
Sleep duration and quality using actigraphic recording.Results:
There were no differences found between groups on the primary outcomes nor on the secondary outcomes (sleepiness, mood, cooperation with therapy).Conclusion:
BWL treatment during acute rehabilitation hospitalization does not appear to impact sleep or measures commonly associated with sleep. While studies have indicated common complaints of sleep difficulties after TBI, we were unable to document an effect for phototherapy as a treatment. With growing evidence of the effect of sleep on neural repair and cognition, further study is needed to understand the nature and treatment of sleep disorders after TBI.Clinicaltrials.gov Identifier NCT02214212.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sleep Wake Disorders
/
Brain Injuries, Traumatic
Type of study:
Clinical_trials
/
Etiology_studies
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Brain Inj
Journal subject:
CEREBRO
Year:
2021
Type:
Article
Affiliation country:
United States