A protocol for rapid pericyte differentiation of human induced pluripotent stem cells.
STAR Protoc
; 2(1): 100261, 2021 03 19.
Article
in En
| MEDLINE
| ID: mdl-33490977
ABSTRACT
Pericytes play a critical role in promoting, regulating, and maintaining numerous vascular functions. Their dysfunction is a major contributor to the progression of vascular and neurodegenerative diseases, making them an ideal candidate for large-scale production for disease modeling and regenerative cell therapy. This protocol describes the rapid and robust differentiation of pericytes from human induced pluripotent stem cells (hiPSCs) while simultaneously generating a population of hiPSC-derived endothelial progenitor cells. For complete details on the use and execution of this protocol, please refer to Zhang et al. (2017).
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cell Differentiation
/
Cell Culture Techniques
/
Pericytes
/
Induced Pluripotent Stem Cells
Type of study:
Guideline
Limits:
Humans
Language:
En
Journal:
STAR Protoc
Year:
2021
Type:
Article
Affiliation country:
United States