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Repeated Administration of Clinically Relevant Doses of the Prescription Opioids Tramadol and Tapentadol Causes Lung, Cardiac, and Brain Toxicity in Wistar Rats.
Barbosa, Joana; Faria, Juliana; Garcez, Fernanda; Leal, Sandra; Afonso, Luís Pedro; Nascimento, Ana Vanessa; Moreira, Roxana; Pereira, Frederico C; Queirós, Odília; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge.
Affiliation
  • Barbosa J; IINFACTS-Institute of Research and Advanced Training in Health Sciences and Technologies, Department of Sciences, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal.
  • Faria J; UCIBIO, REQUIMTE-Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
  • Garcez F; Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
  • Leal S; IINFACTS-Institute of Research and Advanced Training in Health Sciences and Technologies, Department of Sciences, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal.
  • Afonso LP; UCIBIO, REQUIMTE-Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
  • Nascimento AV; IINFACTS-Institute of Research and Advanced Training in Health Sciences and Technologies, Department of Sciences, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal.
  • Moreira R; IINFACTS-Institute of Research and Advanced Training in Health Sciences and Technologies, Department of Sciences, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal.
  • Pereira FC; Department of Biomedicine, Unit of Anatomy, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
  • Queirós O; CINTESIS-Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, 4200-450 Porto, Portugal.
  • Carvalho F; Department of Pathology, Portuguese Institute of Oncology of Porto, 4200-072 Porto, Portugal.
  • Dinis-Oliveira RJ; IINFACTS-Institute of Research and Advanced Training in Health Sciences and Technologies, Department of Sciences, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal.
Pharmaceuticals (Basel) ; 14(2)2021 Jan 27.
Article in En | MEDLINE | ID: mdl-33513867
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies Language: En Journal: Pharmaceuticals (Basel) Year: 2021 Type: Article Affiliation country: Portugal
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies Language: En Journal: Pharmaceuticals (Basel) Year: 2021 Type: Article Affiliation country: Portugal