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RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.
Patel, Parasvi S; Abraham, Karan Joshua; Guturi, Kiran Kumar Naidu; Halaby, Marie-Jo; Khan, Zahra; Palomero, Luis; Ho, Brandon; Duan, Shili; St-Germain, Jonathan; Algouneh, Arash; Mateo, Francesca; El Ghamrasni, Samah; Barbour, Haithem; Barnes, Daniel R; Beesley, Jonathan; Sanchez, Otto; Berman, Hal K; Brown, Grant W; Affar, El Bachir; Chenevix-Trench, Georgia; Antoniou, Antonis C; Arrowsmith, Cheryl H; Raught, Brian; Pujana, Miquel Angel; Mekhail, Karim; Hakem, Anne; Hakem, Razqallah.
Affiliation
  • Patel PS; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • Abraham KJ; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Guturi KKN; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • Halaby MJ; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • Khan Z; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • Palomero L; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Barcelona, Catalonia, Spain.
  • Ho B; Department of Biochemistry and Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Duan S; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • St-Germain J; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • Algouneh A; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Mateo F; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Barcelona, Catalonia, Spain.
  • El Ghamrasni S; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • Barbour H; Centre de Recherche, Hôpital Maisonneuve-Rosemont, Montreal, Quebec, Canada.
  • Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
  • Beesley J; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Sanchez O; University of Ontario Institute of Technology, Oshawa, Ontario, Canada.
  • Berman HK; Toronto General Research Institute, Toronto, Ontario, Canada.
  • Brown GW; Department of Biochemistry and Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Affar EB; Centre de Recherche, Hôpital Maisonneuve-Rosemont, Montreal, Quebec, Canada.
  • Chenevix-Trench G; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
  • Arrowsmith CH; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • Raught B; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • Pujana MA; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Barcelona, Catalonia, Spain.
  • Mekhail K; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Hakem A; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
  • Hakem R; Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.
J Clin Invest ; 131(3)2021 02 01.
Article in En | MEDLINE | ID: mdl-33529165
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / DNA, Neoplasm / Mammary Neoplasms, Animal / BRCA1 Protein / BRCA2 Protein / Genomic Instability / Ubiquitin-Protein Ligases Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: J Clin Invest Year: 2021 Type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / DNA, Neoplasm / Mammary Neoplasms, Animal / BRCA1 Protein / BRCA2 Protein / Genomic Instability / Ubiquitin-Protein Ligases Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: J Clin Invest Year: 2021 Type: Article