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Exploitation of the vitamin A/retinoic acid axis depletes ALDH1-positive cancer stem cells and re-sensitises resistant non-small cell lung cancer cells to cisplatin.
MacDonagh, Lauren; Santiago, Rhyla Mae; Gray, Steven G; Breen, Eamon; Cuffe, Sinead; Finn, Stephen P; O'Byrne, Kenneth J; Barr, Martin P.
Affiliation
  • MacDonagh L; Thoracic Oncology Research Group, School of Clinical Medicine, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, St James's Hospital & Trinity College Dublin, Ireland. Electronic address: lmacdona@tcd.ie.
  • Santiago RM; Thoracic Oncology Research Group, School of Clinical Medicine, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, St James's Hospital & Trinity College Dublin, Ireland. Electronic address: SantiagR@tcd.ie.
  • Gray SG; Thoracic Oncology Research Group, School of Clinical Medicine, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, St James's Hospital & Trinity College Dublin, Ireland. Electronic address: Sgray@stjames.ie.
  • Breen E; Flow Cytometry Facility, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, Trinity College Dublin, Ireland. Electronic address: Breenea@tcd.ie.
  • Cuffe S; Thoracic Oncology Research Group, School of Clinical Medicine, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, St James's Hospital & Trinity College Dublin, Ireland; Medical Oncology Department, St James's Hospital, Dublin, Ireland. Electronic address: Scuffe@stjame
  • Finn SP; Thoracic Oncology Research Group, School of Clinical Medicine, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, St James's Hospital & Trinity College Dublin, Ireland; Histopathology Department, St James's Hospital & Trinity College Dublin, Ireland. Electronic add
  • O'Byrne KJ; Cancer & Ageing Research Program, Queensland University of Technology, Brisbane, Australia. Electronic address: K.obyrne@qut.edu.au.
  • Barr MP; Thoracic Oncology Research Group, School of Clinical Medicine, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, St James's Hospital & Trinity College Dublin, Ireland. Electronic address: mbarr@stjames.ie.
Transl Oncol ; 14(4): 101025, 2021 Apr.
Article in En | MEDLINE | ID: mdl-33550205
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Transl Oncol Year: 2021 Type: Article
Fulltext
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Transl Oncol Year: 2021 Type: Article