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Tbx5 variants disrupt Nav1.5 function differently in patients diagnosed with Brugada or Long QT Syndrome.
Nieto-Marín, Paloma; Tinaquero, David; Utrilla, Raquel G; Cebrián, Jorge; González-Guerra, Andrés; Crespo-García, Teresa; Cámara-Checa, Anabel; Rubio-Alarcón, Marcos; Dago, María; Alfayate, Silvia; Filgueiras-Rama, David; Peinado, Rafael; López-Sendón, José Luis; Jalife, José; Tamargo, Juan; Bernal, Juan Antonio; Caballero, Ricardo; Delpón, Eva.
Affiliation
  • Nieto-Marín P; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • Tinaquero D; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • Utrilla RG; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • Cebrián J; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • González-Guerra A; Fundación Centro Nacional de Investigaciones Cardiovasculares. CIBERCV, Madrid 28029, Spain.
  • Crespo-García T; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • Cámara-Checa A; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • Rubio-Alarcón M; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • Dago M; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • Alfayate S; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • Filgueiras-Rama D; Fundación Centro Nacional de Investigaciones Cardiovasculares. CIBERCV, Madrid 28029, Spain.
  • Peinado R; Department of Cardiology, Hospital Universitario La Paz. Instituto de Investigación Sanitaria la Paz. CIBERCV, Madrid 28046, Spain.
  • López-Sendón JL; Department of Cardiology, Hospital Universitario La Paz. Instituto de Investigación Sanitaria la Paz. CIBERCV, Madrid 28046, Spain.
  • Jalife J; Fundación Centro Nacional de Investigaciones Cardiovasculares. CIBERCV, Madrid 28029, Spain.
  • Tamargo J; Departments of Internal Medicine and Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Bernal JA; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
  • Caballero R; Fundación Centro Nacional de Investigaciones Cardiovasculares. CIBERCV, Madrid 28029, Spain.
  • Delpón E; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid. Instituto de Investigación Gregorio Marañón. CIBERCV, Madrid 28040, Spain.
Cardiovasc Res ; 118(4): 1046-1060, 2022 03 16.
Article in En | MEDLINE | ID: mdl-33576403
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Long QT Syndrome / Brugada Syndrome / Induced Pluripotent Stem Cells Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Cardiovasc Res Year: 2022 Type: Article Affiliation country: Spain
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Long QT Syndrome / Brugada Syndrome / Induced Pluripotent Stem Cells Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Cardiovasc Res Year: 2022 Type: Article Affiliation country: Spain