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Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma.
Da Vià, Matteo C; Dietrich, Oliver; Truger, Marietta; Arampatzi, Panagiota; Duell, Johannes; Heidemeier, Anke; Zhou, Xiang; Danhof, Sophia; Kraus, Sabrina; Chatterjee, Manik; Meggendorfer, Manja; Twardziok, Sven; Goebeler, Maria-Elisabeth; Topp, Max S; Hudecek, Michael; Prommersberger, Sabrina; Hege, Kristen; Kaiser, Shari; Fuhr, Viktoria; Weinhold, Niels; Rosenwald, Andreas; Erhard, Florian; Haferlach, Claudia; Einsele, Hermann; Kortüm, K Martin; Saliba, Antoine-Emmanuel; Rasche, Leo.
Affiliation
  • Da Vià MC; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Dietrich O; Helmholtz Institute for RNA-based Infection Research, Helmholtz-Center for Infection Research, Würzburg, Germany.
  • Truger M; Munich Leukemia Laboratory, Munich, Germany.
  • Arampatzi P; Core Unit Systems Medicine, University of Würzburg, Würzburg, Germany.
  • Duell J; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Heidemeier A; Department of Radiology, University Hospital of Würzburg, Würzburg, Germany.
  • Zhou X; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Danhof S; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Kraus S; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Chatterjee M; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Meggendorfer M; Munich Leukemia Laboratory, Munich, Germany.
  • Twardziok S; Munich Leukemia Laboratory, Munich, Germany.
  • Goebeler ME; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Topp MS; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Hudecek M; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Prommersberger S; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Hege K; Bristol Myers Squibb, San Francisco, CA, USA.
  • Kaiser S; Bristol Myers Squibb, San Francisco, CA, USA.
  • Fuhr V; Institute of Pathology, University of Würzburg, Würzburg, Germany.
  • Weinhold N; Medizinische Klinik 5, University Hospital of Heidelberg, Heidelberg, Germany.
  • Rosenwald A; Institute of Pathology, University of Würzburg, Würzburg, Germany.
  • Erhard F; Institute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.
  • Haferlach C; Munich Leukemia Laboratory, Munich, Germany.
  • Einsele H; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Kortüm KM; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.
  • Saliba AE; Helmholtz Institute for RNA-based Infection Research, Helmholtz-Center for Infection Research, Würzburg, Germany.
  • Rasche L; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany. Rasche_L@ukw.de.
Nat Med ; 27(4): 616-619, 2021 04.
Article in En | MEDLINE | ID: mdl-33619368
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Gene Deletion / B-Cell Maturation Antigen / Receptors, Chimeric Antigen / Multiple Myeloma Type of study: Prognostic_studies / Risk_factors_studies Limits: Aged / Humans / Male Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2021 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Gene Deletion / B-Cell Maturation Antigen / Receptors, Chimeric Antigen / Multiple Myeloma Type of study: Prognostic_studies / Risk_factors_studies Limits: Aged / Humans / Male Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2021 Type: Article Affiliation country: Germany