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SARS-CoV-2 nsp12 attenuates type I interferon production by inhibiting IRF3 nuclear translocation.
Wang, Wenjing; Zhou, Zhuo; Xiao, Xia; Tian, Zhongqin; Dong, Xiaojing; Wang, Conghui; Li, Li; Ren, Lili; Lei, Xiaobo; Xiang, Zichun; Wang, Jianwei.
Affiliation
  • Wang W; NHC Key Laboratory of System Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, PR China.
  • Zhou Z; Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, PR China.
  • Xiao X; Christophe Merieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, PR China.
  • Tian Z; Biomedical Pioneering Innovation Center, Beijing Advanced Innovation Center for Genomics, Peking University Genome Editing Research Center, School of Life Sciences, Peking University, Beijing, 100871, China.
  • Dong X; NHC Key Laboratory of System Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, PR China.
  • Wang C; Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, PR China.
  • Li L; Christophe Merieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, PR China.
  • Ren L; NHC Key Laboratory of System Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, PR China.
  • Lei X; Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, PR China.
  • Xiang Z; Christophe Merieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, PR China.
  • Wang J; NHC Key Laboratory of System Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, PR China.
Cell Mol Immunol ; 18(4): 945-953, 2021 04.
Article in En | MEDLINE | ID: mdl-33637958
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Interferon Regulatory Factor-3 / Coronavirus RNA-Dependent RNA Polymerase / SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: Cell Mol Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Interferon Regulatory Factor-3 / Coronavirus RNA-Dependent RNA Polymerase / SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: Cell Mol Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Type: Article