Cardiac myosin binding protein-C phosphorylation accelerates ß-cardiac myosin detachment rate in mouse myocardium.

Tanner, Bertrand C W; Previs, Michael J; Wang, Yuan; Robbins, Jeffrey; Palmer, Bradley M

Tanner, Bertrand C W; Previs, Michael J; Wang, Yuan; Robbins, Jeffrey; Palmer, Bradley M.

Affiliation

Tanner BCW; Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, Vermont.
Previs MJ; Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, Vermont.
Wang Y; Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, Vermont.
Robbins J; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Palmer BM; Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, Vermont.

Am J Physiol Heart Circ Physiol ; 320(5): H1822-H1835, 2021 05 01.

Article in En | MEDLINE | ID: mdl-33666504

Subject(s)

Carrier Proteins/metabolism; Muscle Strength; Myocardial Contraction; Myocardium/metabolism; Ventricular Myosins/metabolism; Animals; Biomechanical Phenomena; Carrier Proteins/genetics; Cyclic AMP-Dependent Protein Kinases/metabolism; Kinetics; Male; Mice, Knockout; Models, Cardiovascular; Phosphorylation; Protein Binding

Key words

cardiac; myofilament; myosin binding protein-C; step response; stretch activation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carrier Proteins / Ventricular Myosins / Muscle Strength / Myocardial Contraction / Myocardium Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2021 Type: Article

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