Targeting GRK5 for Treating Chronic Degenerative Diseases.

Marzano, Federica; Rapacciuolo, Antonio; Ferrara, Nicola; Rengo, Giuseppe; Koch, Walter J; Cannavo, Alessandro

Marzano, Federica; Rapacciuolo, Antonio; Ferrara, Nicola; Rengo, Giuseppe; Koch, Walter J; Cannavo, Alessandro.

Affiliation

Marzano F; Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Rapacciuolo A; Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Ferrara N; Department of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Rengo G; Istituti Clinici Scientifici Maugeri-Scientific Institute of Telese Terme (BN), 82037 Telese Terme, Italy.
Koch WJ; Department of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Cannavo A; Istituti Clinici Scientifici Maugeri-Scientific Institute of Telese Terme (BN), 82037 Telese Terme, Italy.

Int J Mol Sci ; 22(4)2021 Feb 15.

Article in En | MEDLINE | ID: mdl-33671974

Subject(s)

Cardiovascular Diseases/drug therapy; Cardiovascular Diseases/metabolism; G-Protein-Coupled Receptor Kinase 5/antagonists & inhibitors; G-Protein-Coupled Receptor Kinase 5/metabolism; Molecular Targeted Therapy/methods; Neoplasms/drug therapy; Neoplasms/metabolism; Neurodegenerative Diseases/drug therapy; Neurodegenerative Diseases/metabolism; Animals; G-Protein-Coupled Receptor Kinase 5/chemistry; Humans; Receptors, G-Protein-Coupled/metabolism; Signal Transduction

Key words

GPCR; GRK5; cancer; cardiovascular; neurodegeneration

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiovascular Diseases / Neurodegenerative Diseases / G-Protein-Coupled Receptor Kinase 5 / Molecular Targeted Therapy / Neoplasms Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2021 Type: Article Affiliation country: Italy

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