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Itaconate confers tolerance to late NLRP3 inflammasome activation.
Bambouskova, Monika; Potuckova, Lucie; Paulenda, Tomas; Kerndl, Martina; Mogilenko, Denis A; Lizotte, Kate; Swain, Amanda; Hayes, Sebastian; Sheldon, Ryan D; Kim, Hyeryun; Kapadnis, Unnati; Ellis, Abigail E; Isaguirre, Christine; Burdess, Samantha; Laha, Anwesha; Amarasinghe, Gaya K; Chubukov, Victor; Roddy, Thomas P; Diamond, Michael S; Jones, Russell G; Simons, Donald M; Artyomov, Maxim N.
Affiliation
  • Bambouskova M; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Potuckova L; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Paulenda T; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Kerndl M; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, 1090 Vienna, Austria; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arth
  • Mogilenko DA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Lizotte K; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA 02139, USA.
  • Swain A; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Hayes S; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA 02139, USA.
  • Sheldon RD; Van Andel Research Institute, Metabolic and Nutritional Programming, Center for Cancer and Cell Biology, Grand Rapids, MI 49503, USA.
  • Kim H; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA 02139, USA.
  • Kapadnis U; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA 02139, USA.
  • Ellis AE; Van Andel Research Institute, Metabolic and Nutritional Programming, Center for Cancer and Cell Biology, Grand Rapids, MI 49503, USA.
  • Isaguirre C; Van Andel Research Institute, Metabolic and Nutritional Programming, Center for Cancer and Cell Biology, Grand Rapids, MI 49503, USA.
  • Burdess S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Laha A; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Amarasinghe GK; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Chubukov V; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA 02139, USA.
  • Roddy TP; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA 02139, USA.
  • Diamond MS; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110,
  • Jones RG; Van Andel Research Institute, Metabolic and Nutritional Programming, Center for Cancer and Cell Biology, Grand Rapids, MI 49503, USA.
  • Simons DM; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA 02139, USA.
  • Artyomov MN; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: martyomov@wustl.edu.
Cell Rep ; 34(10): 108756, 2021 03 09.
Article in En | MEDLINE | ID: mdl-33691097
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Succinates / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein Limits: Animals Language: En Journal: Cell Rep Year: 2021 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Succinates / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein Limits: Animals Language: En Journal: Cell Rep Year: 2021 Type: Article Affiliation country: United States