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Talimogene laherparepvec upregulates immune-cell populations in non-injected lesions: findings from a phase II, multicenter, open-label study in patients with stage IIIB-IVM1c melanoma.
Malvehy, Josep; Samoylenko, Igor; Schadendorf, Dirk; Gutzmer, Ralf; Grob, Jean-Jacques; Sacco, Joseph J; Gorski, Kevin S; Anderson, Abraham; Pickett, Cheryl A; Liu, Kate; Gogas, Helen.
Affiliation
  • Malvehy J; Dermatology Department and IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Catalunya, Spain JMALVEHY@clinic.cat.
  • Samoylenko I; NN Blokhin Russian Cancer Research Center, Moscow, Russian Federation.
  • Schadendorf D; Department of Dermatology, University of Duisburg-Essen, Essen, Germany.
  • Gutzmer R; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Grob JJ; Department of Dermatology and Allergy, Skin Cancer Center Hannover, Hannover Medical School, Hannover, Germany.
  • Sacco JJ; Aix-Marseille University and APHM Timone, Marseille, France.
  • Gorski KS; Clatterbridge Cancer Centre NHS Foundation Trust, Bebington, Wirral, UK.
  • Anderson A; University of Liverpool, Liverpool, UK.
  • Pickett CA; Amgen Inc, San Francisco, California, USA.
  • Liu K; Amgen Inc, Thousand Oaks, California, USA.
  • Gogas H; Amgen Inc, Thousand Oaks, California, USA.
J Immunother Cancer ; 9(3)2021 03.
Article in En | MEDLINE | ID: mdl-33785610

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Biological Products / Lymphocytes, Tumor-Infiltrating / Herpesvirus 1, Human / CD8-Positive T-Lymphocytes / Oncolytic Viruses / Oncolytic Virotherapy / Tumor Microenvironment / Melanoma Type of study: Clinical_trials / Diagnostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: J Immunother Cancer Year: 2021 Type: Article Affiliation country: Spain

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Biological Products / Lymphocytes, Tumor-Infiltrating / Herpesvirus 1, Human / CD8-Positive T-Lymphocytes / Oncolytic Viruses / Oncolytic Virotherapy / Tumor Microenvironment / Melanoma Type of study: Clinical_trials / Diagnostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: J Immunother Cancer Year: 2021 Type: Article Affiliation country: Spain