The Metabolic Fates of Pyruvate in Normal and Neoplastic Cells.

Prochownik, Edward V; Wang, Huabo

Prochownik, Edward V; Wang, Huabo.

Affiliation

Prochownik EV; Division of Hematology/Oncology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA 15224, USA.
Wang H; The Department of Microbiology and Molecular Genetics, UPMC, Pittsburgh, PA 15213, USA.

Cells ; 10(4)2021 03 30.

Article in En | MEDLINE | ID: mdl-33808495

Subject(s)

Neoplasms/metabolism; Neoplasms/pathology; Pyruvic Acid/metabolism; Acetates/metabolism; Animals; Biosynthetic Pathways; Embryonic Development; Humans; Tumor Microenvironment

Key words

TCA cycle; Warburg effect; anaplerosis; glutaminolysis; lactate dehydrogenase; malic enzyme; pyruvate carboxylase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyruvic Acid / Neoplasms Limits: Animals / Humans Language: En Journal: Cells Year: 2021 Type: Article Affiliation country: United States

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