Defective Reelin/Dab1 signaling pathways associated with disturbed hippocampus development of homozygous yotari mice.

Arimitsu, Nagisa; Mizukami, Yoshihisa; Shimizu, Jun; Takai, Kenji; Suzuki, Tomoko; Suzuki, Noboru

Arimitsu, Nagisa; Mizukami, Yoshihisa; Shimizu, Jun; Takai, Kenji; Suzuki, Tomoko; Suzuki, Noboru.

Affiliation

Arimitsu N; Department of Immunology and Medicine, St. Marianna University School of Medicine, Sugao 2-16-1, Miyamae-ku, Kawasaki 216-8511, Japan.
Mizukami Y; Department of Immunology and Medicine, St. Marianna University School of Medicine, Sugao 2-16-1, Miyamae-ku, Kawasaki 216-8511, Japan.
Shimizu J; Department of Immunology and Medicine, St. Marianna University School of Medicine, Sugao 2-16-1, Miyamae-ku, Kawasaki 216-8511, Japan.
Takai K; Department of Immunology and Medicine, St. Marianna University School of Medicine, Sugao 2-16-1, Miyamae-ku, Kawasaki 216-8511, Japan.
Suzuki T; Department of Immunology and Medicine, St. Marianna University School of Medicine, Sugao 2-16-1, Miyamae-ku, Kawasaki 216-8511, Japan.
Suzuki N; Department of Immunology and Medicine, St. Marianna University School of Medicine, Sugao 2-16-1, Miyamae-ku, Kawasaki 216-8511, Japan. Electronic address: n3suzuki@marianna-u.ac.jp.

Mol Cell Neurosci ; 112: 103614, 2021 04.

Article in En | MEDLINE | ID: mdl-33845123

Subject(s)

Cell Adhesion Molecules, Neuronal/physiology; Extracellular Matrix Proteins/physiology; Hippocampus/abnormalities; Mice, Mutant Strains/abnormalities; Nerve Tissue Proteins/physiology; Serine Endopeptidases/physiology; Signal Transduction/physiology; Animals; Cell Adhesion Molecules, Neuronal/deficiency; Cell Movement; Enzyme Activation; Extracellular Matrix Proteins/deficiency; Genes, Recessive; Hippocampus/embryology; Hippocampus/metabolism; Hippocampus/pathology; Homozygote; Mice; Mice, Mutant Strains/genetics; Mice, Mutant Strains/metabolism; Nerve Tissue Proteins/biosynthesis; Nerve Tissue Proteins/deficiency; Nerve Tissue Proteins/genetics; Neural Cell Adhesion Molecules/biosynthesis; Neural Cell Adhesion Molecules/genetics; Phenotype; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt/metabolism; Reelin Protein; Serine Endopeptidases/deficiency; Synapses/metabolism; Transcription Factors/biosynthesis; Transcription Factors/genetics

Key words

Akt, Hippocampus; Brain development; Disabled 1; yotari mouse

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine Endopeptidases / Signal Transduction / Cell Adhesion Molecules, Neuronal / Extracellular Matrix Proteins / Hippocampus / Mice, Mutant Strains / Nerve Tissue Proteins Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Mol Cell Neurosci Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2021 Type: Article Affiliation country: Japan

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