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Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment.
Poznanski, Sophie M; Singh, Kanwaldeep; Ritchie, Tyrah M; Aguiar, Jennifer A; Fan, Isabella Y; Portillo, Ana L; Rojas, Eduardo A; Vahedi, Fatemeh; El-Sayes, Abdullah; Xing, Sansi; Butcher, Martin; Lu, Yu; Doxey, Andrew C; Schertzer, Jonathan D; Hirte, Hal W; Ashkar, Ali A.
Affiliation
  • Poznanski SM; Department of Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8N 3Z5, Canada.
  • Singh K; Department of Oncology, McMaster University, Hamilton, ON L8V 5C2, Canada.
  • Ritchie TM; Department of Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8N 3Z5, Canada.
  • Aguiar JA; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
  • Fan IY; Department of Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8N 3Z5, Canada.
  • Portillo AL; Department of Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8N 3Z5, Canada.
  • Rojas EA; Department of Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8N 3Z5, Canada.
  • Vahedi F; Department of Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8N 3Z5, Canada.
  • El-Sayes A; Department of Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8N 3Z5, Canada.
  • Xing S; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.
  • Butcher M; Juravinski Cancer Centre & McMaster University, Hamilton, ON L8V 5C2, Canada.
  • Lu Y; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.
  • Doxey AC; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
  • Schertzer JD; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada; Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada.
  • Hirte HW; Department of Oncology, McMaster University, Hamilton, ON L8V 5C2, Canada; Division of Medical Oncology, Juravinski Cancer Centre, Hamilton, ON L8V 5C2, Canada.
  • Ashkar AA; Department of Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8N 3Z5, Canada. Electronic address: ashkara@mcmaster.ca.
Cell Metab ; 33(6): 1205-1220.e5, 2021 06 01.
Article in En | MEDLINE | ID: mdl-33852875
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / Tumor Microenvironment / Immunotherapy / Neoplasms / Antineoplastic Agents Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Cell Metab Journal subject: METABOLISMO Year: 2021 Type: Article Affiliation country: Canada
Fulltext
Print
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PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / Tumor Microenvironment / Immunotherapy / Neoplasms / Antineoplastic Agents Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Cell Metab Journal subject: METABOLISMO Year: 2021 Type: Article Affiliation country: Canada