Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology.

Terrey, Markus; Adamson, Scott I; Chuang, Jeffrey H; Ackerman, Susan L

Terrey, Markus; Adamson, Scott I; Chuang, Jeffrey H; Ackerman, Susan L.

Affiliation

Terrey M; Howard Hughes Medical Institute, Department of Cellular and Molecular Medicine, Section of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, United States.
Adamson SI; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, United States.
Chuang JH; The Jackson Laboratory for Genomic Medicine, Farmington, United States.
Ackerman SL; Department of Genetics and Genome Sciences, Institute for Systems Genomics, UConn Health, Farmington, United States.

Elife ; 102021 04 26.

Article in En | MEDLINE | ID: mdl-33899734

Subject(s)

Cell Cycle Proteins/genetics; Cerebellum/growth & development; Endonucleases/genetics; GTP-Binding Proteins/genetics; Neurogenesis/genetics; Neurons/physiology; Peptide Chain Termination, Translational/genetics; Animals; Cell Cycle Proteins/metabolism; Endonucleases/metabolism; Female; GTP-Binding Proteins/metabolism; Male; Mice; Mice, Knockout

Key words

cerebellum; chromosomes; gene expression; mouse; n-Tr20; neurogenesis; ribosome; translation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Chain Termination, Translational / Cerebellum / Cell Cycle Proteins / GTP-Binding Proteins / Endonucleases / Neurogenesis / Neurons Limits: Animals Language: En Journal: Elife Year: 2021 Type: Article Affiliation country: United States

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