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Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells.
Orzalli, Megan H; Prochera, Aleksandra; Payne, Laurellee; Smith, Avi; Garlick, Jonathan A; Kagan, Jonathan C.
Affiliation
  • Orzalli MH; Program in Innate Immunity, Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA; Division of Gastroenterology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: megan.orzalli@
  • Prochera A; Division of Gastroenterology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA; Program in Immunology, Harvard Medical School, Longwood Avenue, Boston, MA, USA.
  • Payne L; Program in Innate Immunity, Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
  • Smith A; Department of Diagnostic Sciences, Tufts University School of Dental Medicine, Boston, MA, USA.
  • Garlick JA; Department of Diagnostic Sciences, Tufts University School of Dental Medicine, Boston, MA, USA; Sackler Graduate School of Biomedical Sciences, Tufts University, Boston, MA, USA.
  • Kagan JC; Division of Gastroenterology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA; Program in Immunology, Harvard Medical School, Longwood Avenue, Boston, MA, USA. Electronic address: jonathan.kagan@childrens.harvard.edu.
Immunity ; 54(7): 1447-1462.e5, 2021 07 13.
Article in En | MEDLINE | ID: mdl-33979579

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viruses / Receptors, Estrogen / Apoptosis / Proto-Oncogene Proteins c-bcl-2 / Epithelial Cells / Pyroptosis Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viruses / Receptors, Estrogen / Apoptosis / Proto-Oncogene Proteins c-bcl-2 / Epithelial Cells / Pyroptosis Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Type: Article