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Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection.
Knudson, Cory J; Alves-Peixoto, Pedro; Muramatsu, Hiromi; Stotesbury, Colby; Tang, Lingjuan; Lin, Paulo J C; Tam, Ying K; Weissman, Drew; Pardi, Norbert; Sigal, Luis J.
Affiliation
  • Knudson CJ; Department of Microbiology and Immunology, Bluemle Life Science Building, Thomas Jefferson University, Philadelphia, PA 19107, USA.
  • Alves-Peixoto P; Department of Microbiology and Immunology, Bluemle Life Science Building, Thomas Jefferson University, Philadelphia, PA 19107, USA; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga 4710-057, Portugal; ICVS/3B's-PT Government Associate Laboratory, Bra
  • Muramatsu H; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Stotesbury C; Department of Microbiology and Immunology, Bluemle Life Science Building, Thomas Jefferson University, Philadelphia, PA 19107, USA.
  • Tang L; Department of Microbiology and Immunology, Bluemle Life Science Building, Thomas Jefferson University, Philadelphia, PA 19107, USA.
  • Lin PJC; Acuitas Therapeutics, Vancouver, BC V6T 1Z3, Canada.
  • Tam YK; Acuitas Therapeutics, Vancouver, BC V6T 1Z3, Canada.
  • Weissman D; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Pardi N; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Sigal LJ; Department of Microbiology and Immunology, Bluemle Life Science Building, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address: luis.sigal@jefferson.edu.
Mol Ther ; 29(9): 2769-2781, 2021 09 01.
Article in En | MEDLINE | ID: mdl-33992803
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Ectromelia, Infectious / CD8-Positive T-Lymphocytes / Ectromelia virus / MRNA Vaccines Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2021 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Ectromelia, Infectious / CD8-Positive T-Lymphocytes / Ectromelia virus / MRNA Vaccines Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2021 Type: Article Affiliation country: United States