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Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.
Sharif, Humayun; Hollingsworth, L Robert; Griswold, Andrew R; Hsiao, Jeffrey C; Wang, Qinghui; Bachovchin, Daniel A; Wu, Hao.
Affiliation
  • Sharif H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
  • Hollingsworth LR; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA.
  • Griswold AR; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA; Pharmacology Program, Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Hsiao JC; Pharmacology Program, Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Wang Q; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Bachovchin DA; Pharmacology Program, Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: bachovcd@mskcc.org.
  • Wu H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA. Electronic address: wu@crystal.harvard.edu.
Immunity ; 54(7): 1392-1404.e10, 2021 07 13.
Article in En | MEDLINE | ID: mdl-34019797
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / CARD Signaling Adaptor Proteins / Inflammasomes / Neoplasm Proteins Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / CARD Signaling Adaptor Proteins / Inflammasomes / Neoplasm Proteins Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Type: Article Affiliation country: United States