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DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A.
Leon, Kelly E; Buj, Raquel; Lesko, Elizabeth; Dahl, Erika S; Chen, Chi-Wei; Tangudu, Naveen Kumar; Imamura-Kawasawa, Yuka; Kossenkov, Andrew V; Hobbs, Ryan P; Aird, Katherine M.
Affiliation
  • Leon KE; Department of Pharmacology and Chemical Biology, University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.
  • Buj R; Biomedical Sciences Graduate Program, Penn State College of Medicine, Hershey, PA.
  • Lesko E; Department of Pharmacology and Chemical Biology, University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.
  • Dahl ES; Department of Dermatology, Penn State College of Medicine, Hershey, PA.
  • Chen CW; Biomedical Sciences Graduate Program, Penn State College of Medicine, Hershey, PA.
  • Tangudu NK; Department of Pharmacology and Chemical Biology, University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.
  • Imamura-Kawasawa Y; Department of Pharmacology and Chemical Biology, University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.
  • Kossenkov AV; Department of Pharmacology, Penn State College of Medicine, Hershey, PA.
  • Hobbs RP; The Wistar Institute, Philadelphia, PA.
  • Aird KM; Department of Dermatology, Penn State College of Medicine, Hershey, PA.
J Cell Biol ; 220(8)2021 08 02.
Article in En | MEDLINE | ID: mdl-34037658

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / Histone-Lysine N-Methyltransferase / Cellular Senescence / DNA Methylation / Epigenesis, Genetic / Interleukin-1alpha / Fibroblasts Type of study: Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: J Cell Biol Year: 2021 Type: Article Affiliation country: Panama

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / Histone-Lysine N-Methyltransferase / Cellular Senescence / DNA Methylation / Epigenesis, Genetic / Interleukin-1alpha / Fibroblasts Type of study: Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: J Cell Biol Year: 2021 Type: Article Affiliation country: Panama