Sclerosing cholangitis in a patient treated with nivolumab.
BMJ Case Rep
; 14(5)2021 May 28.
Article
in En
| MEDLINE
| ID: mdl-34049893
ABSTRACT
A 69-year-old retired miner with stage 4 non-small-cell lung cancer presented with a 2-month history of obstructive liver function tests following nivolumab immunotherapy. His case had not responded to high dose prednisolone or mycophenolate and he was admitted for investigation. MR cholangiopancreatography demonstrated areas of intrahepatic biliary tree beading and stricturing, in keeping with sclerosing cholangitis. Prednisolone and mycophenolate were stopped and ursodeoxycholic acid commenced with subsequent partial improvement of the patient's liver function tests.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cholangitis, Sclerosing
/
Carcinoma, Non-Small-Cell Lung
/
Lung Neoplasms
Limits:
Aged
/
Humans
/
Male
Language:
En
Journal:
BMJ Case Rep
Year:
2021
Type:
Article
Affiliation country:
United kingdom