Extensive C->U transition biases in the genomes of a wide range of mammalian RNA viruses; potential associations with transcriptional mutations, damage- or host-mediated editing of viral RNA.

Simmonds, Peter; Ansari, M Azim

Simmonds, Peter; Ansari, M Azim.

Affiliation

Simmonds P; Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Ansari MA; Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.

PLoS Pathog ; 17(6): e1009596, 2021 06.

Article in En | MEDLINE | ID: mdl-34061905

Subject(s)

Mammals/virology; Mutation; RNA Viruses/genetics; SARS-CoV-2/genetics; APOBEC Deaminases/metabolism; Animals; Base Sequence; COVID-19/virology; Cytidine/genetics; DNA Damage/physiology; Evolution, Molecular; Gene Expression Regulation, Viral; Genome, Viral; Host-Pathogen Interactions/genetics; Humans; Nucleic Acid Conformation; Phylogeny; RNA Editing/physiology; RNA Viruses/classification; RNA, Viral/chemistry; RNA, Viral/genetics; SARS-CoV-2/chemistry; SARS-CoV-2/classification; Sequence Analysis, RNA; Transcription, Genetic/genetics; Uridine/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA Viruses / SARS-CoV-2 / Mammals / Mutation Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2021 Type: Article Affiliation country: United kingdom

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