Metabolic engineering of Escherichia coli for de novo production of 3-phenylpropanol via retrobiosynthesis approach.

Liu, Zhenning; Zhang, Xue; Lei, Dengwei; Qiao, Bin; Zhao, Guang-Rong

Liu, Zhenning; Zhang, Xue; Lei, Dengwei; Qiao, Bin; Zhao, Guang-Rong.

Affiliation

Liu Z; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin, 300350, China.
Zhang X; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin, 300350, China.
Lei D; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin, 300350, China.
Qiao B; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin, 300350, China.
Zhao GR; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin, 300350, China. grzhao@tju.edu.cn.

Microb Cell Fact ; 20(1): 121, 2021 Jun 27.

Article in En | MEDLINE | ID: mdl-34176467

Subject(s)

Biosynthetic Pathways; Escherichia coli/genetics; Escherichia coli/metabolism; Genetic Engineering/methods; Metabolic Engineering/methods; Phenylalanine/metabolism; Propanols/metabolism; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Fermentation; Gene Editing; Industrial Microbiology/methods; Oxidoreductases/genetics; Oxidoreductases/metabolism; Phenylalanine Ammonia-Lyase/genetics; Phenylalanine Ammonia-Lyase/metabolism; Transferases (Other Substituted Phosphate Groups)/genetics; Transferases (Other Substituted Phosphate Groups)/metabolism

Key words

3-Phenylpropanol; Escherichia coli; Metabolic engineering; Retrobiosynthesis; Synthetic biology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylalanine / Genetic Engineering / Propanols / Escherichia coli / Biosynthetic Pathways / Metabolic Engineering Language: En Journal: Microb Cell Fact Journal subject: BIOTECNOLOGIA / MICROBIOLOGIA Year: 2021 Type: Article Affiliation country: China

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