Single-Center Comparison of Outcomes Following Cardiac Surgery in Low Birth Weight and Standard Birth Weight Neonates.
J Pediatr
; 238: 161-167.e1, 2021 11.
Article
in En
| MEDLINE
| ID: mdl-34214588
ABSTRACT
OBJECTIVE:
To compare outcomes between low birth weight (LBW; <2.5 kg) and standard birth weight neonates undergoing cardiac surgery. STUDYDESIGN:
A single-center retrospective study of neonates undergoing cardiac surgery with cardiopulmonary bypass from 2012 to 2018. LBW neonates were 12 propensity score-matched to standard birth weight neonates (n = 93 to n = 186) using clinical characteristics. The primary and secondary outcomes were survival to hospital discharge and postoperative complications, respectively. After matching, regression analyses were conducted to compare outcomes.RESULTS:
The LBW group had a higher proportion of premature neonates than the standard birth weight group (60% vs 8%; P < .01) and were less likely to survive to hospital discharge (88% vs 95%; OR, 0.39; 95% CI, 0.15-0.97). There was no difference in unplanned cardiac reoperations or catheter-based interventions, cardiac arrest, extracorporeal membrane oxygenation, infection, and end-organ complications between the groups. Among LBW infants, survival was improved at weight >2 kg.CONCLUSIONS:
LBW is a risk factor for decreased survival. LBW neonates weighing >2 kg have survival comparable to those weighing >2.5 kg.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Heart Defects, Congenital
/
Cardiac Surgical Procedures
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Humans
/
Infant
/
Newborn
Language:
En
Journal:
J Pediatr
Year:
2021
Type:
Article