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Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence.
Joy, Jery; Barrio, Lara; Santos-Tapia, Celia; Romão, Daniela; Giakoumakis, Nikolaos Nikiforos; Clemente-Ruiz, Marta; Milán, Marco.
Affiliation
  • Joy J; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028 Barcelona, Spain.
  • Barrio L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028 Barcelona, Spain.
  • Santos-Tapia C; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028 Barcelona, Spain.
  • Romão D; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028 Barcelona, Spain.
  • Giakoumakis NN; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028 Barcelona, Spain.
  • Clemente-Ruiz M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028 Barcelona, Spain.
  • Milán M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028 Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Pg. Lluís Companys 23, 08010 Barcelona, Spain. Electronic address: marco.milan@irbbarcelona.
Dev Cell ; 56(14): 2043-2058.e7, 2021 07 26.
Article in En | MEDLINE | ID: mdl-34216545
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cellular Senescence / JNK Mitogen-Activated Protein Kinases / Drosophila melanogaster / Mitophagy / Proteostasis / Aneuploidy / Mitochondria Limits: Animals Language: En Journal: Dev Cell Journal subject: EMBRIOLOGIA Year: 2021 Type: Article Affiliation country: Spain
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cellular Senescence / JNK Mitogen-Activated Protein Kinases / Drosophila melanogaster / Mitophagy / Proteostasis / Aneuploidy / Mitochondria Limits: Animals Language: En Journal: Dev Cell Journal subject: EMBRIOLOGIA Year: 2021 Type: Article Affiliation country: Spain