Single-cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human-specific features.

Rayon, Teresa; Maizels, Rory J; Barrington, Christopher; Briscoe, James

Rayon, Teresa; Maizels, Rory J; Barrington, Christopher; Briscoe, James.

Affiliation

Rayon T; The Francis Crick Institute, London NW1 1AT, UK.
Maizels RJ; The Francis Crick Institute, London NW1 1AT, UK.
Barrington C; The Francis Crick Institute, London NW1 1AT, UK.
Briscoe J; The Francis Crick Institute, London NW1 1AT, UK.

Development ; 148(15)2021 08 01.

Article in En | MEDLINE | ID: mdl-34351410

Subject(s)

Spinal Cord/physiology; Transcriptome/genetics; Transcriptome/physiology; Animals; Cell Differentiation/physiology; Embryo, Mammalian/physiology; Ganglia, Spinal/physiology; Gene Expression/genetics; Gene Expression Profiling/methods; Humans; Mice; Motor Neurons/physiology; Neural Tube/physiology; Sensory Receptor Cells/physiology; Thorax/physiology

Key words

Developmental patterning; Human; Neuronal subtype identity; Single-cell transcriptome; Spinal cord

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord / Transcriptome Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2021 Type: Article Affiliation country: United kingdom

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