RIM-Binding Protein 2 Organizes Ca<sup>2+</sup> Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse.

Butola, Tanvi; Alvanos, Theocharis; Hintze, Anika; Koppensteiner, Peter; Kleindienst, David; Shigemoto, Ryuichi; Wichmann, Carolin; Moser, Tobias

RIM-Binding Protein 2 Organizes Ca²⁺ Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse.

Butola, Tanvi; Alvanos, Theocharis; Hintze, Anika; Koppensteiner, Peter; Kleindienst, David; Shigemoto, Ryuichi; Wichmann, Carolin; Moser, Tobias.

Affiliation

Butola T; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen 37075, Germany.
Alvanos T; Synaptic Nanophysiology Group, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Hintze A; International Max Planck Research School for Neurosciences and Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), University of Göttingen, 37075 Göttingen, Germany.
Koppensteiner P; Collaborative Research Center 1286, University of Göttingen, 37075 Göttingen, Germany.
Kleindienst D; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen 37075, Germany.
Shigemoto R; Synaptic Nanophysiology Group, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Wichmann C; International Max Planck Research School for Neurosciences and Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), University of Göttingen, 37075 Göttingen, Germany.
Moser T; Collaborative Research Center 1286, University of Göttingen, 37075 Göttingen, Germany.

J Neurosci ; 41(37): 7742-7767, 2021 09 15.

Article in En | MEDLINE | ID: mdl-34353898

Subject(s)

Calcium Channels/metabolism; Intracellular Signaling Peptides and Proteins/metabolism; Neurons/metabolism; Synapses/metabolism; Synaptic Vesicles/metabolism; Animals; Calcium/metabolism; Intracellular Signaling Peptides and Proteins/genetics; Mice; Mice, Knockout; Neuronal Plasticity/physiology; Synaptic Transmission/physiology

Key words

CaV2.1 control of transmitter release; RIM-binding protein 2; active zone topography; calyceal synapses; endbulb of Held; short-term plasticity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Synaptic Vesicles / Calcium Channels / Intracellular Signaling Peptides and Proteins / Neurons Limits: Animals Language: En Journal: J Neurosci Year: 2021 Type: Article Affiliation country: Germany

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