Positive predictive value highlights four novel candidates for actionable genetic screening from analysis of 220,000 clinicogenomic records.

Schiabor Barrett, Kelly M; Bolze, Alexandre; Ni, Yunyun; White, Simon; Isaksson, Magnus; Sharma, Lavania; Levin, Elissa; Lee, William; Grzymski, Joseph J; Lu, James T; Washington, Nicole L; Cirulli, Elizabeth T

Schiabor Barrett, Kelly M; Bolze, Alexandre; Ni, Yunyun; White, Simon; Isaksson, Magnus; Sharma, Lavania; Levin, Elissa; Lee, William; Grzymski, Joseph J; Lu, James T; Washington, Nicole L; Cirulli, Elizabeth T.

Affiliation

Schiabor Barrett KM; Helix, San Mateo, CA, USA.
Bolze A; Helix, San Mateo, CA, USA.
Ni Y; Helix, San Mateo, CA, USA.
White S; Helix, San Mateo, CA, USA.
Isaksson M; Helix, San Mateo, CA, USA.
Sharma L; Helix, San Mateo, CA, USA.
Levin E; Helix, San Mateo, CA, USA.
Lee W; Helix, San Mateo, CA, USA.
Grzymski JJ; Renown Institute for Health Innovation, Reno, NV, USA.
Lu JT; Desert Research Institute, Reno, NV, USA.
Washington NL; Helix, San Mateo, CA, USA.
Cirulli ET; Helix, San Mateo, CA, USA.

Genet Med ; 23(12): 2300-2308, 2021 12.

Article in En | MEDLINE | ID: mdl-34385667

Subject(s)

Genes, BRCA2; Genetic Testing; Exome; Genetic Predisposition to Disease; Humans; Predictive Value of Tests; Exome Sequencing

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Testing / Genes, BRCA2 Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Humans Language: En Journal: Genet Med Journal subject: GENETICA MEDICA Year: 2021 Type: Article Affiliation country: United States

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