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Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function.
Salter, Alexander I; Rajan, Anusha; Kennedy, Jacob J; Ivey, Richard G; Shelby, Sarah A; Leung, Isabel; Templeton, Megan L; Muhunthan, Vishaka; Voillet, Valentin; Sommermeyer, Daniel; Whiteaker, Jeffrey R; Gottardo, Raphael; Veatch, Sarah L; Paulovich, Amanda G; Riddell, Stanley R.
Affiliation
  • Salter AI; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. asalter@fhcrc.org sriddell@fhcrc.org.
  • Rajan A; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Kennedy JJ; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Ivey RG; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Shelby SA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Leung I; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Templeton ML; Department of Biophysics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Muhunthan V; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Voillet V; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Sommermeyer D; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Whiteaker JR; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Gottardo R; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Veatch SL; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Paulovich AG; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Riddell SR; Cape Town HVTN Immunology Laboratory, Hutchinson Centre Research Institute of South Africa, NPC (HCRISA), Cape Town 8001, South Africa.
Sci Signal ; 14(697)2021 08 24.
Article in En | MEDLINE | ID: mdl-34429382

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Chimeric Antigen / Multiple Myeloma Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2021 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Chimeric Antigen / Multiple Myeloma Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2021 Type: Article