Down-regulated MicroRNAs in Gastric Carcinoma May Be Targets for Therapeutic Intervention and Replacement Therapy.

Weidle, Ulrich H; Birzele, Fabian; Auslaender, Simon; Brinkmann, Ulrich

Weidle, Ulrich H; Birzele, Fabian; Auslaender, Simon; Brinkmann, Ulrich.

Affiliation

Weidle UH; Large Molecule Research, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Munich, Penzberg, Germany.
Birzele F; Pharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.
Auslaender S; Large Molecule Research, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Munich, Penzberg, Germany.
Brinkmann U; Large Molecule Research, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Munich, Penzberg, Germany; ulrich.brinkmann@roche.com weidle49@t-online.de.

Anticancer Res ; 41(9): 4185-4202, 2021 Sep.

Article in En | MEDLINE | ID: mdl-34475038

Subject(s)

Down-Regulation; MicroRNAs/genetics; Stomach Neoplasms/genetics; Antineoplastic Agents/pharmacology; Antineoplastic Agents/therapeutic use; Gene Expression Regulation, Neoplastic/drug effects; Gene Regulatory Networks; Humans; Molecular Targeted Therapy; Stomach Neoplasms/drug therapy

Key words

Cell-cycle/apoptosis; functional characteristics of targets; prognosis; review.; small GTPases-related and -associated molecules; target validation; tractability; transcription factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Down-Regulation / MicroRNAs Type of study: Prognostic_studies Limits: Humans Language: En Journal: Anticancer Res Year: 2021 Type: Article Affiliation country: Germany

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