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Novel vancomycin resistance gene cluster in Enterococcus faecium ST1486, Belgium, June 2021.
Xavier, Basil Britto; Coppens, Jasmine; De Koster, Sien; Rajakani, Sahaya Glingston; Van Goethem, Sam; Mzougui, Samy; Anantharajah, Ahalieyah; Lammens, Christine; Loens, Katherine; Glupczynski, Youri; Goossens, Herman; Matheeussen, Veerle.
Affiliation
  • Xavier BB; Laboratory of Medical Microbiology, Universiteit Antwerpen, Wilrijk, Belgium.
  • Coppens J; Vaccine and Infectious Disease Institute, Universiteit Antwerpen, Wilrijk, Belgium.
  • De Koster S; Laboratory of Clinical Microbiology, Antwerp University Hospital, Edegem, Belgium.
  • Rajakani SG; Laboratory of Medical Microbiology, Universiteit Antwerpen, Wilrijk, Belgium.
  • Van Goethem S; Vaccine and Infectious Disease Institute, Universiteit Antwerpen, Wilrijk, Belgium.
  • Mzougui S; Laboratory of Medical Microbiology, Universiteit Antwerpen, Wilrijk, Belgium.
  • Anantharajah A; Vaccine and Infectious Disease Institute, Universiteit Antwerpen, Wilrijk, Belgium.
  • Lammens C; Laboratory of Clinical Microbiology, Antwerp University Hospital, Edegem, Belgium.
  • Loens K; Laboratory of Clinical Microbiology, Cliniques Universitaires Saint-Luc-UCLouvain, Brussels, Belgium.
  • Glupczynski Y; Laboratory of Clinical Microbiology, Cliniques Universitaires Saint-Luc-UCLouvain, Brussels, Belgium.
  • Goossens H; Laboratory of Medical Microbiology, Universiteit Antwerpen, Wilrijk, Belgium.
  • Matheeussen V; Vaccine and Infectious Disease Institute, Universiteit Antwerpen, Wilrijk, Belgium.
Euro Surveill ; 26(36)2021 09.
Article in En | MEDLINE | ID: mdl-34505571
ABSTRACT
We identified a novel van gene cluster in a clinical Enterococcus faecium isolate with vancomycin minimum inhibitory concentration (MIC) of 4 µg/mL. The ligase gene, vanP, was part of a van operon cluster of 4,589 bp on a putative novel integrative conjugative element located in a ca 98 kb genomic region presumed to be acquired by horizontal gene transfer from Clostridiumscidens and Roseburia sp. 499. Screening for van genes in E. faecium strains with borderline susceptibility to vancomycin is important.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enterococcus faecium Limits: Humans Country/Region as subject: Europa Language: En Journal: Euro Surveill Journal subject: DOENCAS TRANSMISSIVEIS Year: 2021 Type: Article Affiliation country: Belgium
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enterococcus faecium Limits: Humans Country/Region as subject: Europa Language: En Journal: Euro Surveill Journal subject: DOENCAS TRANSMISSIVEIS Year: 2021 Type: Article Affiliation country: Belgium