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A hypolipoprotein sepsis phenotype indicates reduced lipoprotein antioxidant capacity, increased endothelial dysfunction and organ failure, and worse clinical outcomes.
Guirgis, Faheem W; Black, Lauren Page; Henson, Morgan; Labilloy, Guillaume; Smotherman, Carmen; Hopson, Charlotte; Tfirn, Ian; DeVos, Elizabeth L; Leeuwenburgh, Christiaan; Moldawer, Lyle; Datta, Susmita; Brusko, Todd M; Hester, Alexis; Bertrand, Andrew; Grijalva, Victor; Arango-Esterhay, Alexander; Moore, Frederick A; Reddy, Srinivasa T.
Affiliation
  • Guirgis FW; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA. Faheem.Guirgis@jax.ufl.edu.
  • Black LP; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.
  • Henson M; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.
  • Labilloy G; Center for Data Solutions, University of Florida College of Medicine - Jacksonville, Jacksonville, FL, USA.
  • Smotherman C; Center for Data Solutions, University of Florida College of Medicine - Jacksonville, Jacksonville, FL, USA.
  • Hopson C; Center for Data Solutions, University of Florida College of Medicine - Jacksonville, Jacksonville, FL, USA.
  • Tfirn I; Center for Data Solutions, University of Florida College of Medicine - Jacksonville, Jacksonville, FL, USA.
  • DeVos EL; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.
  • Leeuwenburgh C; Department of Aging and Geriatric Research, University of Florida College of Medicine, Gainesville, FL, USA.
  • Moldawer L; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
  • Datta S; Department of Biostatistics, University of Florida, Gainesville, FL, USA.
  • Brusko TM; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL, USA.
  • Hester A; Department of Pediatrics, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL, USA.
  • Bertrand A; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.
  • Grijalva V; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.
  • Arango-Esterhay A; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
  • Moore FA; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.
  • Reddy ST; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
Crit Care ; 25(1): 341, 2021 09 17.
Article in En | MEDLINE | ID: mdl-34535154

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Outcome Assessment, Health Care / Sepsis / Lipoproteins / Multiple Organ Failure / Antioxidants Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Crit Care Year: 2021 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Outcome Assessment, Health Care / Sepsis / Lipoproteins / Multiple Organ Failure / Antioxidants Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Crit Care Year: 2021 Type: Article Affiliation country: United States