Low Ozone Concentrations Differentially Affect the Structural and Functional Features of Non-Activated and Activated Fibroblasts In Vitro.

Cisterna, Barbara; Costanzo, Manuela; Lacavalla, Maria Assunta; Galiè, Mirco; Angelini, Osvaldo; Tabaracci, Gabriele; Malatesta, Manuela

Cisterna, Barbara; Costanzo, Manuela; Lacavalla, Maria Assunta; Galiè, Mirco; Angelini, Osvaldo; Tabaracci, Gabriele; Malatesta, Manuela.

Affiliation

Cisterna B; Department of Neurosciences, Biomedicine and Movement Sciences, Anatomy and Histology Section, University of Verona, Strada Le Grazie 8, I-37134 Verona, Italy.
Costanzo M; Department of Neurosciences, Biomedicine and Movement Sciences, Anatomy and Histology Section, University of Verona, Strada Le Grazie 8, I-37134 Verona, Italy.
Lacavalla MA; Department of Neurosciences, Biomedicine and Movement Sciences, Anatomy and Histology Section, University of Verona, Strada Le Grazie 8, I-37134 Verona, Italy.
Galiè M; Department of Neurosciences, Biomedicine and Movement Sciences, Anatomy and Histology Section, University of Verona, Strada Le Grazie 8, I-37134 Verona, Italy.
Angelini O; San Rocco Clinic, Via Monsignor G.V. Moreni 95, I-25018 Montichari, Italy.
Tabaracci G; San Rocco Clinic, Via Monsignor G.V. Moreni 95, I-25018 Montichari, Italy.
Malatesta M; Department of Neurosciences, Biomedicine and Movement Sciences, Anatomy and Histology Section, University of Verona, Strada Le Grazie 8, I-37134 Verona, Italy.

Int J Mol Sci ; 22(18)2021 Sep 20.

Article in En | MEDLINE | ID: mdl-34576295

Subject(s)

Fibroblasts/drug effects; Oxidants, Photochemical/pharmacology; Ozone/pharmacology; Cell Line; Cell Proliferation; Fibroblasts/metabolism; Fibroblasts/physiology; Fibroblasts/ultrastructure; Heme Oxygenase-1/metabolism; Humans; Interleukin-6/metabolism; Lipopolysaccharides/pharmacology; NF-E2-Related Factor 2/metabolism; Oxidative Stress; Transforming Growth Factor beta/metabolism

Key words

cell proliferation; cell surface protrusions; fluorescence microscopy; heme oxygenase 1 (Hmox1) gene; interleukin-6; nuclear factor erythroid 2-related factor 2 (Nrf2); oxygenozone therapy; real-time quantitative polymerase chain reaction (RT-qPCR); scanning electron microscopy; transforming growth factor (TGF)-ß1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidants, Photochemical / Ozone / Fibroblasts Type of study: Prognostic_studies Limits: Humans Language: En Journal: Int J Mol Sci Year: 2021 Type: Article Affiliation country: Italy

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