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Two new triterpenoids from the fruits of Aphanamixis polystachya.
Wu, Shi-Li; Zou, Qiu-Ping; Xie, Xiao-Yan; Ren, Jia-Jia; Fan, Zhang; OuYang, Jing-Rong; Yin, Peng-Cheng; Dong, Fa-Wu; He, Hong-Ping.
Affiliation
  • Wu SL; College of Chinese Materia Medica and Yunnan Key Laboratory of Southen Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
  • Zou QP; College of Chinese Materia Medica and Yunnan Key Laboratory of Southen Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
  • Xie XY; College of Chinese Materia Medica and Yunnan Key Laboratory of Southen Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
  • Ren JJ; College of Chinese Materia Medica and Yunnan Key Laboratory of Southen Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
  • Fan Z; College of Chinese Materia Medica and Yunnan Key Laboratory of Southen Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
  • OuYang JR; College of Chinese Materia Medica and Yunnan Key Laboratory of Southen Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
  • Yin PC; College of Chinese Materia Medica and Yunnan Key Laboratory of Southen Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
  • Dong FW; College of Chinese Materia Medica and Yunnan Key Laboratory of Southen Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
  • He HP; College of Chinese Materia Medica and Yunnan Key Laboratory of Southen Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
J Asian Nat Prod Res ; 24(8): 738-745, 2022 Aug.
Article in En | MEDLINE | ID: mdl-34581235
ABSTRACT
Two new triucallane triterpenoids, polystanin F (1) and polystanin G (2), along with eight known compounds (3-10) were isolated from the fruits of Aphanamixis polystachya. Their structures were established on the basis of extensive spectroscopic analysis. Moreover, eight compounds were evaluated for their in vitro cytotoxicity against three cancer cell lines (liver cancer RT112, colon cancer HCT-116 and breast cancer M231) using the MTT method. Compound 7 showed significant cytotoxic activity against HCT-116 with IC50 1.27 µM.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Meliaceae / Limonins Language: En Journal: J Asian Nat Prod Res Journal subject: BOTANICA / QUIMICA Year: 2022 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Meliaceae / Limonins Language: En Journal: J Asian Nat Prod Res Journal subject: BOTANICA / QUIMICA Year: 2022 Type: Article Affiliation country: China