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BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.
Kang, Zhihua; Fu, Pan; Alcivar, Allen L; Fu, Haiqing; Redon, Christophe; Foo, Tzeh Keong; Zuo, Yamei; Ye, Caiyong; Baxley, Ryan; Madireddy, Advaitha; Buisson, Remi; Bielinsky, Anja-Katrin; Zou, Lee; Shen, Zhiyuan; Aladjem, Mirit I; Xia, Bing.
Affiliation
  • Kang Z; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Fu P; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Alcivar AL; Department of Clinical Microbiology Laboratory, Children's Hospital of Fudan University, Shanghai, China.
  • Fu H; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Redon C; Bristol-Myers Squibb Company, Bloomsbury, NJ, 08804, USA.
  • Foo TK; Developmental Therapeutics Group, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Zuo Y; Developmental Therapeutics Group, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Ye C; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Baxley R; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Madireddy A; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Buisson R; School of Radiation Medicine and Protection, Soochow University, Suzhou, China.
  • Bielinsky AK; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, USA.
  • Zou L; Department of Pediatric Hematology/Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Shen Z; Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA, USA.
  • Aladjem MI; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.
  • Xia B; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, USA.
Nat Commun ; 12(1): 5966, 2021 10 13.
Article in En | MEDLINE | ID: mdl-34645815

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Neoplasm / DNA, Single-Stranded / DNA Primase / BRCA2 Protein / DNA-Directed DNA Polymerase / Recombinational DNA Repair / Minichromosome Maintenance Proteins / Multifunctional Enzymes Type of study: Risk_factors_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Neoplasm / DNA, Single-Stranded / DNA Primase / BRCA2 Protein / DNA-Directed DNA Polymerase / Recombinational DNA Repair / Minichromosome Maintenance Proteins / Multifunctional Enzymes Type of study: Risk_factors_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: United States